Biologic Excipients Market Introduction

 Biologic excipients are substances that are added to biologic formulations to enhance their stability, bioavailability, and efficacy. They are used in the manufacturing of biologics such as vaccines, gene therapies, and biopharmaceuticals. Biologic excipients serve as the delivery system for the active pharmaceutical ingredient (API) and play a critical role in ensuring the safe and effective delivery of the drug to the patient. Some examples of biologic excipients include stabilizers, surfactants, emulsifiers, and solvents. The biologic excipients market is an essential component of the biopharmaceutical industry, which is driven by the increasing demand for effective biologics to treat chronic and life-threatening diseases

Biologic Excipients Market  Size

The biologic excipients market is expected to grow in the coming years. The global biologic excipients market was valued at USD 1.8 billion in 2020 and is projected to reach USD 3.5 billion by 2028, growing at a CAGR of 8.5% during the forecast period of 2021-2028.The growth of the market is driven by several factors, including the increasing demand for biologics, the rise in the prevalence of chronic diseases, the growing adoption of biosimilars, and the need for efficient drug delivery systems. In addition, the development of novel excipients and the increasing investments by pharmaceutical companies in research and development activities are also expected to contribute to the growth of the market.Based on product type, the market can be segmented into polymers, sugar alcohols, amino acids, surfactants, and others. Polymers are expected to dominate the market due to their versatile properties and wide range of applications in biologic formulations.Geographically, North America is expected to dominate the market due to the presence of a large number of biopharmaceutical companies and the high adoption of biologics. However, the Asia Pacific region is expected to witness the highest growth during the forecast period due to the increasing investments in the biopharmaceutical industry and the rising demand for biologics in the region.Overall, the biologic excipients market is expected to witness significant growth in the coming years, driven by the increasing demand for biologics and the need for efficient drug delivery systems.

Biologic Excipients Market  Share

The biologic excipients market is highly fragmented, with several players operating in the market. Some of the key players in the market include:

1. Ashland Global Holdings Inc.
2. BASF SE
3. DowDuPont Inc.
4. Evonik Industries AG
5. Roquette Freres
6. Croda International Plc
7. Lubrizol Corporation
8. Wacker Chemie AG
9. ABITEC Corporation
10. Signet Chemical Corporation Pvt. Ltd.

Ashland Global Holdings Inc. and BASF SE are among the leading players in the market, owing to their broad product portfolio and global presence. Other players in the market are also expanding their product portfolio through strategic partnerships and collaborations with biopharmaceutical companies. For instance, in 2020, Croda International Plc announced a collaboration with Pfizer Inc. to develop novel excipients for the formulation of biologics.Based on application, the market can be segmented into vaccines, monoclonal antibodies, gene therapies, and others. Monoclonal antibodies are expected to dominate the market due to their high demand in the treatment of various diseases, including cancer and autoimmune disorders.Geographically, North America is expected to hold the largest share of the market due to the presence of a large number of biopharmaceutical companies and the high adoption of biologics. Europe is also expected to hold a significant share of the market due to the increasing demand for biosimilars and the development of novel excipients.Overall, the biologic excipients market is highly competitive, with several players operating in the market. The leading players are expanding their product portfolio through strategic partnerships and collaborations, while other players are focusing on the development of novel excipients to gain a competitive edge in the market.

Biologic Excipients Market Trends

Some of the key trends in the biologic excipients market include:

1. Growing demand for biologics: Biologics are increasingly being used in the treatment of various diseases, including cancer, autoimmune disorders, and genetic disorders. As a result, there is a growing demand for biologic excipients that can improve the stability, solubility, and bioavailability of biologic drugs.
2. Increasing focus on novel excipients: Biopharmaceutical companies are increasingly focusing on the development of novel excipients that can improve the performance of biologic drugs. Novel excipients can help to address the challenges associated with the formulation of biologics, such as stability, viscosity, and aggregation.
3. Adoption of single-use systems: Single-use systems are increasingly being adopted in the biopharmaceutical industry due to their flexibility, cost-effectiveness, and reduced risk of cross-contamination. As a result, there is a growing demand for single-use bioreactors, which require specialized excipients that are compatible with the materials used in the single-use systems.
4. Shift towards outsourcing: Biopharmaceutical companies are increasingly outsourcing their manufacturing operations to contract development and manufacturing organizations (CDMOs). This trend is driving the demand for high-quality excipients that can be used in a variety of biologic drug formulations.
5. Increasing use of biosimilars: Biosimilars are gaining acceptance as a cost-effective alternative to branded biologics. Biosimilars require specialized excipients that can ensure the safety and efficacy of the drug. As a result, there is a growing demand for excipients that are compatible with biosimilars.

Overall, the biologic excipients market is driven by the increasing demand for biologics, the development of novel excipients, the adoption of single-use systems, the shift towards outsourcing, and the increasing use of biosimilars. These trends are expected to continue to shape the market in the coming years.

Biologic Excipients Market Driving factors

There are several factors driving the growth of the biologic excipients market:

1. Increasing demand for biologics: Biologics are a rapidly growing segment of the pharmaceutical industry, with a wide range of applications in the treatment of cancer, autoimmune diseases, and other conditions. Biologic excipients play a critical role in the formulation and delivery of biologics, and the increasing demand for biologics is driving the growth of the biologic excipients market.
2. Growing adoption of biosimilars: Biosimilars are an important segment of the biopharmaceutical market, offering cost-effective alternatives to branded biologics. Biosimilars require specialized excipients to ensure their safety and efficacy, and the growing adoption of biosimilars is driving the demand for biologic excipients.
3. Development of novel excipients: The development of new and innovative biologic excipients is another key driver of the market. Biopharmaceutical companies are investing in the development of new excipients that can improve the stability, solubility, and bioavailability of biologics, and these novel excipients are driving the growth of the market.
4. Increasing outsourcing of biologic manufacturing: Many biopharmaceutical companies are outsourcing their manufacturing operations to contract development and manufacturing organizations (CDMOs) to reduce costs and increase efficiency. This trend is driving the demand for high-quality biologic excipients that can be used in a variety of drug formulations.
5. Favorable regulatory environment: The regulatory environment for biologic excipients is becoming more favorable, with regulators providing clearer guidelines and requirements for the use of excipients in biologics. This is creating new opportunities for biologic excipient manufacturers and driving the growth of the market.

Overall, the increasing demand for biologics, the growing adoption of biosimilars, the development of novel excipients, the increasing outsourcing of biologic manufacturing, and the favorable regulatory environment are all driving the growth of the biologic excipients market.

Biologic Excipients Market  Reginal Analysis

The biologic excipients market can be analyzed by region, with the following regions being the most prominent:

1. North America: The North American market for biologic excipients is driven by the presence of a large biopharmaceutical industry and a favorable regulatory environment. The United States is the largest market in the region, with a well-established biopharmaceutical industry and a large number of biologic drug approvals.
2. Europe: The European market for biologic excipients is driven by the presence of a large biopharmaceutical industry and a growing demand for biosimilars. The European Union has established clear regulatory guidelines for the approval of biosimilars, which is driving the growth of the market.
3. Asia-Pacific: The Asia-Pacific market for biologic excipients is driven by the growth of the biopharmaceutical industry in countries like China and India. These countries have large populations and growing economies, which are driving the demand for biologic drugs and biologic excipients.
4. Latin America: The Latin American market for biologic excipients is driven by the growth of the biopharmaceutical industry in countries like Brazil and Mexico. These countries have large populations and growing economies, which are driving the demand for biologic drugs and biologic excipients.
5. Middle East and Africa: The Middle East and Africa market for biologic excipients is driven by the increasing demand for biologic drugs in the region. The Middle East has a growing healthcare industry and a high prevalence of chronic diseases, which is driving the demand for biologic drugs and biologic excipients.

Overall, the biologic excipients market is expected to grow in all regions, driven by the increasing demand for biologic drugs and the development of novel excipients.

Biologic Excipients Market  Forecasts 2030

The biologic excipients market is expected to continue growing over the next decade, driven by the increasing demand for biologic drugs and the development of new excipients. The global biologic excipients market size was valued at $1.4 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 4.8% from 2021 to 2028. By 2028, the market size is expected to reach $2.1 billion.The report also predicts that the polysorbates segment will continue to dominate the market, accounting for the largest share of revenue due to their widespread use in the formulation of biologic drugs. Other segments such as sugars, amino acids, and polyols are also expected to experience significant growth due to their unique properties and applications in biologic drug formulations.Geographically, the Asia-Pacific region is expected to experience the highest growth rate during the forecast period, driven by the growing biopharmaceutical industry in countries like China and India. However, North America and Europe are expected to remain the largest markets due to the presence of established biopharmaceutical industries and favorable regulatory environments.Overall, the biologic excipients market is expected to continue growing as the demand for biologic drugs increases and as new excipients are developed to improve the safety and efficacy of biologic drug formulations.

Biologic Excipients Market Key Industry Players

Some of the key players operating in the biologic excipients market include:

1. Ashland Global Holdings Inc.
2. BASF SE
3. DowDuPont Inc.
4. Evonik Industries AG
5. Merck KGaA
6. Roquette Freres
7. Kerry Group plc
8. Croda International plc
9. Lubrizol Corporation
10. Innophos Inc.

These companies are actively involved in research and development activities to introduce new and innovative excipients for biologic drug formulations. They are also engaged in strategic partnerships, mergers and acquisitions, and collaborations to expand their market share and global presence.